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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. A pharmacotherapy specialist wishes to investigate the impact of thiazolidinedione therapy on Weight gain. The specialist will determine average body weight immediately before participants begin therapy with pioglitazone and again after they complete 12 weeks of treatment. Which of the following statistical methods is most appropriate for analyzing these data?

A) Unpaired t test
B) Fisher's exact test
C) Paired t test
D) Chi-square test

2. A 69-year-old Woman with chronic liver disease treated with furosemide and potassium chloride for ascites and peripheral edema presents with weakness and fatigue. Her serum laboratory Values are:
* Sodium: 138 mEq/L
* Potassium: 2.6 mEq/L
* Glucose: 88 mg/dL
* BUN: 33 mg/dL
* Chloride: 101 mEq/L
* HCO3- 26 mEq/L
* Creatinine: 1.1 mg/dL
Attempts to increase her serum potassium over the next 48 hours include intravenous replacement (240 mEq over this period), without success. The current serum potassium concentration is 2.8 mEq/L. Which of the following is the most appropriate test to obtain for this patient?

A) Urinary potassium
B) Urinary sodium
C) Serum magnesium
D) Serum antidiuretic hormone

3. A 13-year-old boy who has asthma, weight 32kg, height 150cm, takes inhaled salmeterol one puff twice daily and inhaled fluticasone 2 puffs twice daily. The patient must stop participation in physical education classes after a few minutes due to shortness of breath. To allow the patient to participate longer, the most effective measure would be to add which of the following?

A) Inhaled cromolyn 30-60 minutes prior to class
B) An extra dose of inhaled salmeterol 30-60 minutes before class
C) Inhaled albuterol 15 minutes before class
D) An extra dose of inhaled fluticasone 1-2 hours before class

4. The most efficient approach for comparing the efficacy of treatments for BPH is to search which of the following?

A) Drug Facts & Comparisons
B) Cochrane Systematic Reviews
C) Lexicomp's Drug information Handbook
D) MEDLINE for clinical trials

5. A 21-year-old patient with leukemia is admitted to the hospital with a temperature of 38.9°C and a nonproductive cough 8 days after induction chemotherapy completion. Laboratory tests show a WBC count of 1,000 cells/ul (10% segmented neutrophils, 0% bands, and 90% lymphocytes) and a platelet count of 60,000 cells/uL. Chest X-ray reveals a small left lower lobe infiltrate. Blood, urine, and sputum cultures are obtained. What should be the recommendation for initial management?

A) Initiate cefepime, Vancomycin, and tobramycin.
B) Initiate amphotericin, ceftazidime, and gentamicin.
C) Initiate fluconazole, vancomycin, and imipenem.
D) Hold antibiotics until Culture results are available.

Solutions: